MBTPS2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-52057
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | BRESEK,Endopeptidase S2P,IFAP,KFSDX,MBTP2,MBTPS2,Membrane bound transcription factor site 2 protease,membrane-bound transcription factor peptidase, site 2,membrane-bound transcription factor protease, site 2,Membrane-bound transcription factor site-2 protease,S2P,S2P endopeptidase,Site 2 protease,SREBPs intramembrane protease,Sterol regulatory element-binding proteins intramembrane protease,MBTPS2抗体 |
| Swissprot | O43462 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human MBTPS2 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:10-1:50; |
| Concentration | 0.9mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane. Cytoplasm. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response. |
