MCM7 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-40231
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | CDABP0042,CDC 47,CDC47,CDC47 homolog,Cdc47, S. cerevisiae, homolog of,DNA replication licensing factor MCM7,Homolog of S. cerevisiae Cdc47,MCM 2,MCM 7,MCM2,MCM2, formerly,Mcm7,MCM7 minichromosome maintenance deficient 7,MCM7_HUMAN,Minichromosome Maintainence 7,Minichromosome maintainence, S. cerevisiae, homolog of,Minichromosome maintenance complex component 7,Minichromosome maintenance deficient 7,Minichromosome maintenance protein 7,P1.1 MCM3,P1.1-MCM3,P1CDC47,P85MCM,PNAS 146,PNAS146,PPP1R104,Protein phosphatase 1, regulatory subunit 104,MCM7抗体 |
| Swissprot | P33993 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant Human DNA replication licensing factor MCM7 protien |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 2mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus |
| Tissue specificity | Highest expression level in embryo |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4 |
| Background | The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. |
