MCPH1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18549
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | BRCT repeat inhibitor of TERT expression 1,BRIT 1,FLJ12847,Hypothetical protein FLJ12847,MCPH 1,MCPH1,MCPH1,MCT,Microcephalin 1,Microcephalin,Microcephaly primary autosomal recessive 1,MCPH1抗体 |
| Swissprot | Q8NEM0 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Fusion protein of human MCPH1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:300 |
| Concentration | 0.9mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm>cytoskeleton>centrosome. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described. |
