MDFI Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18801
宿主: Rabbit
反应性: H,R
应用: WB,IHC
Overview
| Synonyms | I MF,I mfa,Inhibitor of MyoD family a,Mdfi,MDFI,MyoD family inhibitor,Myogenic repressor I-mf,OTTHUMP00000016375,OTTHUMP00000016376,OTTHUMP00000196103,OTTHUMP00000196414,OTTHUMP00000196415,MDFI抗体 |
| Swissprot | Q99750 |
| Source | Rabbit |
| Reactivity | Human,Rat |
| Immunogen | Fusion protein of human MDFI |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:300; |
| Concentration | 0.96mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. Cytoplasm. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.MDFI (MyoD Family Inhibitor) is a Protein Coding gene. GO annotations related to this gene include transcription factor binding. An important paralog of this gene is MDFIC. |
Images
Western blot analysis of Human placenta tissue lysate using MDFI Polyclonal Antibody at dilution of 1:400
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using MDFI Polyclonal Antibody at dilution of 1:55(×200)
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using MDFI Polyclonal Antibody at dilution of 1:55(×200)
