MECOM Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19826
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | Ecotropic Virus Integration Site 1 Protein Homolog,MDS1 And EVI1 Complex Locus Protein,PR Domain 3,EVI1,MDS1,MDS1 And EVI1 Complex Locus Protein EVI1,MDS1 And EVI1 Complex Locus Protein MDS1,Ecotropic Viral Integration Site 1,Myelodysplasia Syndrome 1 Protein,Zinc Finger Protein Evi1,Oncogene EVI1,AML1-EVI-1,MDS1-EVI1,RUSAT2,KMT8E,PRDM3,MECOM抗体 |
| Swissprot | Q03112 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human MECOM |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:40-1:200 |
| Concentration | 1.68mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm, Nucleus |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. |
