MEF2C Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-40236
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
Synonyms | C5DELq14.3,DEL5q14.3,MADS box transcription enhancer factor 2 polypeptide C (myocyte enhancer factor 2C),MEF2C,Myocyte enhancer factor 2C, Myocyte specific enhancer factor 2C,OTTHUMP00000222409,Similar to MADS box transcription enhancer factor 2 polypeptide C,MEF2C抗体 |
Swissprot | Q06413 |
Source | Rabbit |
Reactivity | Human,Mouse |
Immunogen | Recombinant Human Myocyte-specific enhancer factor 2C protien |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC 1:50-1:200 |
Concentration | 2mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Nucleus |
Tissue specificity | Expressed in brain and skeletal muscle. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% Proclin300, 50% glycerol, pH7.4. |
Background | This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe cognitive disability, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described. |