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MEF2C Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-40236

宿主: Rabbit

反应性: H,M

应用: IHC

  • 详情
  • Overview

    Synonyms C5DELq14.3,DEL5q14.3,MADS box transcription enhancer factor 2 polypeptide C (myocyte enhancer factor 2C),MEF2C,Myocyte enhancer factor 2C, Myocyte specific enhancer factor 2C,OTTHUMP00000222409,Similar to MADS box transcription enhancer factor 2 polypeptide C,MEF2C抗体
    Swissprot Q06413
    Source Rabbit
    Reactivity Human,Mouse
    Immunogen Recombinant Human Myocyte-specific enhancer factor 2C protien
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC 1:50-1:200
    Concentration 2mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Nucleus
    Tissue specificity Expressed in brain and skeletal muscle.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% Proclin300, 50% glycerol, pH7.4.
    Background This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe cognitive disability, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described.
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