MIDN Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-12568
宿主: Rabbit
反应性: H,M
应用: WB
Overview
Synonyms | Midbrain nucleolar protein,midn,MIDN,Midnolin,MIDN抗体 |
Swissprot | Q504T8 |
Source | Rabbit |
Reactivity | Human,Mouse |
Immunogen | Synthetic peptide of human MIDN |
Application | WB(Detection kit: E-IR-R304) |
Recommended dilution | WB,,1:500-1:2000; |
Concentration | 0.3 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Nucleus>nucleolus. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | Expression of the midnolin gene is developmentally regulated: it is strongly expressed at the mesencephalon (midbrain) of the embryo in day 12.5 (E12.5) mice.The midnolin encodes a protein of 508 amino acids (aa), which contains a Ubiquitin-like domain.The intracellular distribution of the midnolin was studied by using midnolin-green fluorescent protein (GFP) fusion proteins.Midnolin was found to be localized in the nucleus and nucleolus, but not in the cytoplasm.The nucleolar localization signal was determined to be a 28aa peptide located at the C-terminal region of the midnolin.May be involved in regulation of genes related to neurogenesis in the nucleolus |