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MIDN Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-12568

宿主: Rabbit

反应性: H,M

应用: WB

  • 详情
  • Overview

    Synonyms Midbrain nucleolar protein,midn,MIDN,Midnolin,MIDN抗体
    Swissprot Q504T8
    Source Rabbit
    Reactivity Human,Mouse
    Immunogen Synthetic peptide of human MIDN
    Application WB(Detection kit: E-IR-R304)
    Recommended dilution WB,,1:500-1:2000;
    Concentration 0.3 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Nucleus>nucleolus.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background Expression of the midnolin gene is developmentally regulated: it is strongly expressed at the mesencephalon (midbrain) of the embryo in day 12.5 (E12.5) mice.The midnolin encodes a protein of 508 amino acids (aa), which contains a Ubiquitin-like domain.The intracellular distribution of the midnolin was studied by using midnolin-green fluorescent protein (GFP) fusion proteins.Midnolin was found to be localized in the nucleus and nucleolus, but not in the cytoplasm.The nucleolar localization signal was determined to be a 28aa peptide located at the C-terminal region of the midnolin.May be involved in regulation of genes related to neurogenesis in the nucleolus
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