MMP13 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-10064
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | CLG 3,CLG3,Collagenase 3,Collagenase3,MANDP1,Matrix metallopeptidase 13 (collagenase 3),Matrix Metalloproteinase 13,Matrix metalloproteinase-13,MMP 13,MMP-13,Mmp13,MMP13,MMP13抗体 |
| Swissprot | P45452 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human MMP13 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.4 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted>extracellular space>extracellular matrix. |
| Tissue specificity | Seems to be specific to breast carcinomas. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. |
Images
Western Blot analysis of Hela cell using MMP13 Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human liver cancer using MMP13 Polyclonal Antibody at dilution of 1:10
Immunohistochemistry of paraffin-embedded Human stomach cancer using MMP13 Polyclonal Antibody at dilution of 1:10
客户发表文献
- 文献: on TNF-α induced inflammation in human chondrocytes and SW1353 cells: a possible role for toll-like receptors
样品类型: Cell culture supernatant
