MMP1 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-10061
宿主: Rabbit
反应性: H
应用: IHC
Overview
Synonyms | 27 kDa interstitial collagenase,CLG,CLGN,collagenase,fibroblast,collagenase,interstitial,Fibroblast collagenase,Interstitial collagenase,Matrix metallopeptidase 1 (interstitial collagenase),Matrix metalloprotease 1,Matrix Metalloproteinase 1,Matrix metalloproteinase-1,MMP 1,MMP-1,MMP1,MMP1,OTTHUMP00000045866,MMP1抗体 |
Swissprot | P03956 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Recombinant protein of human MMP1 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:50-1:200 |
Concentration | 0.4 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Secreted>extracellular space>extracellular matrix. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants. |