MMP7 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-10062
宿主: Rabbit
反应性: H
应用: WB
Overview
| Synonyms | Matrilysin,Matrin,Matrix Metalloproteinase 7,Matrix metalloproteinase-7,MMP 7,MMP-7,MMP7,MMP7,MPSL1,PUMP 1,Pump 1 protease,Pump-1 protease,PUMP1,Uterine matrilysin,Uterine metalloproteinase,MMP7抗体 |
| Swissprot | P09237 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant protein of human MMP7 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted>extracellular space>extracellular matrix. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. |
