MORC2 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-18319
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
Synonyms | AC004542.C22.1.,CW type with coiled coil domain 1,KIAA0852,MORC family CW type zinc finger 2,MORC family CW-type zinc finger protein 2,MORC2,MORC2,ZCW3,ZCWCC1,Zinc finger,Zinc finger CW type coiled coil domain protein 1,Zinc finger CW type with coiled coil domain 1,Zinc finger CW-type coiled-coil domain protein 1,Zing finger CW type 3,MORC2抗体 |
Swissprot | Q9Y6X9 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Fusion protein of human MORC2 |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:25-1:100; |
Concentration | 0.5mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Nucleus. Cytoplasm, cytosol. Mainly located in the nucleus. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | The CW domain is a structural module found in many vertebrate, parasitic and plant proteins. It consists of a mononuclear four-cysteine zinc-finger domain that plays a role in DNA binding, chromatin methylation and early embryonic development. ZCWCC1 (zinc finger CW-type coiled-coil domain protein 1), also known as MORC2 (MORC family CW-type zinc finger protein 2) or ZCW3, is a 1,032 amino acid protein that contains one CW-type zinc finger domain. ZCWCC1 is located on chromosome 22 and is ubiquitously expressed with highest expression in pancreas, smooth muscle and testis. Expression of ZCWCC1 is upregulated in hypoxia, a pathological condition characterized by an inadequate supply of oxygen in the blood. |