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MPG Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-14767

宿主: Rabbit

反应性: H

应用: WB

  • 详情
  • Overview

    Synonyms 3 alkyladenine DNA glycosylase,3-alkyladenine DNA glycosylase,3-methyladenine DNA glycosidase,3MG,AAG,ADPG,Alkyladenine DNA glycosylase,anpg,APNG,CRA36.1,DNA 3 methyladenine glycosylase,DNA-3-methyladenine glycosylase,MDG,Mid1,Mpg,N methylpurine DNA glycosirase,N methylpurine DNA glycosylase,N-methylpurine-DNA glycosylase,PIG11,PIG16,Proliferation inducing protein 11,Proliferation inducing protein 16,MPG抗体
    Swissprot P29372
    Source Rabbit
    Reactivity Human
    Immunogen Recombinant protein of human MPG
    Application WB(Detection kit: E-IR-R304)
    Recommended dilution WB,,1:1000-1:5000;
    Concentration 0.7 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Nucleus.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background Maintenance of DNA sequences is necessary for vertebrates and other life.DNA is under constant stress by a plethora of DNA-damaging agents present in both the environment and within cells.The potentially deleterious effects of DNA lesions in cells are elegantly resolved by sophisticated DNA repair systems, including base excision repair (BER), nucleotide excision repair (NER) and DNA repair methyltransferase (MTase).Methylated bases, such as 3-methyladenine (3MeA) and 7-methylguanine (7MeG) can be formed by agents in the environment and by endogenous cellular processes.Consequently, in the absence of exposure to environmental agents, DNA methylation damage can be incurred on the genomic DNA of normal mammalian cells.DNA N-glycosylases are base excision-repair proteins that locate and cleave damaged bases from DNA as the first step in restoring the sequence.
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