MRPL40 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19169
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
| Synonyms | 39S ribosomal protein L40,39S ribosomal protein L40 mitochondrial,39S ribosomal protein L40,mitochondrial precursor,FLJ41774,L40mt,MGC9400,mitochondrial,Mitochondrial ribosomal protein L40,MRP 40,MRP L22,MRP-L40,MRP40,MRPL22,MRPL40,NLVCF,Nuclear localization signal containing protein deleted in velocardiofacial syndrome,Nuclear localization signal deleted in velocardiofacial syndrome,Nuclear localization signal-containing protein deleted in velocardiofacial syndrome,RM40,Up-regulated in metastasis,URIM,MRPL40抗体 |
| Swissprot | Q9NQ50 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Fusion protein of human MRPL40 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:1000-1:5000;IHC,,1:100-1:300; |
| Concentration | 1.44mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Mitochondrion. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome.MRPL40 (Mitochondrial Ribosomal Protein L40) is a Protein Coding gene. Diseases associated with MRPL40 include Mrpl40-Related Disorder and Velocardiofacial Syndrome. Among its related pathways are Mitochondrial translation and Organelle biogenesis and maintenance. GO annotations related to this gene include poly(A) RNA binding. |
Images
Western blot analysis of K562 A172 Jurkat LOVO cell lysates using MRPL40 Polyclonal Antibody at dilution of 1:1000
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using MRPL40 Polyclonal Antibody at dilution of 1:80(×200)
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MRPL40 Polyclonal Antibody at dilution of 1:80(×200)
