MSH4 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-14223
宿主: Rabbit
反应性: H,M
应用: IHC,ELISA
Overview
| Synonyms | hMSH4,MSH 4,MSH4,MSH4,MutS homolog 4 (E. Coli),MutS homolog 4,MutS protein homolog 4,MSH4抗体 |
| Swissprot | O15457 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Recombinant protein of human MSH4 |
| Application | IHC(Detection kit: E-IR-R213),ELISA |
| Recommended dilution | IHC 1:100-1:300 |
| Concentration | 0.5 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus,recombination nodule,synaptonemal complex |
| Tissue specificity | Testis and ovary specific. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a member of the DNA mismatch repair mutS family. This member is a meiosis-specific protein that is not involved in DNA mismatch correction, but is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I. This protein and MSH5 form a heterodimer which binds uniquely to a Holliday Junction and its developmental progenitor, thus provoking ADP-ATP exchange, and stabilizing the interaction between parental chromosomes during meiosis double-stranded break repair. |
