MSLN Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-10472
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | CAK 1,CAK1,CAK1 antigen,cleaved form,Megakaryocyte potentiating factor,Mesothelin,Mesothelin isoform 1 precursor,MPF,Msln,MSLN,Pre pro megakaryocyte potentiating factor,Pre-pro-megakaryocyte-potentiating factor,SMR,SMRP,Soluble MPF mesothelin related protein,MSLN抗体 |
| Swissprot | Q13421 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant protein of human MSLN |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 0.4 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted and Cell membrane. Golgi apparatus. |
| Tissue specificity | Expressed in lung. Expressed at low levels in heart, placenta and kidney. Expressed in mesothelial cells. Highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level). |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants. |
