MUC5AC Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-15787
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | Apomucin,Apomucin Major Airway Glycoprotein,Gastric mucin,LeB,Lewis B blood group antigen,Major Airway Glycoprotein,MUC 5,MUC5,MUC5AC,Mucin 5 subtype AC tracheobronchial,Mucin 5 Subtypes A And C,Mucin 5 subtypes A and C tracheobronchial/gastric,Mucin 5,tracheobronchial/gastric,Mucin 5AC,Mucin 5AC oligomeric mucus/gel forming,Mucin 5AC,oligomeric mucus/gel forming pseudogene,Mucin,TBM,Tracheobronchial Mucin (TBM),Tracheobronchial mucin,MUC5AC抗体 |
| Swissprot | P98088 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human MUC5AC |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 0.8 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted; Cytoplasmic and cell surface |
| Tissue specificity | Highly expressed in surface mucosal cells of respiratory tract and stomach epithelia. Overexpressed in a number of carcinomas. Also expressed in Barrett's esophagus epithelium and in the proximal duodenum. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Mucin-5AC is a protein that in humans is encoded by the MUC5AC gene.This gene has been linked to mucus hypersecretion in the pulmonary tracts and associated to chronic obstructive pulmonary disease (COPD).Gel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particles that are subsequently removed by the mucocilary system.Highly expressed in surface mucosal cells of respiratory tract and stomach epithelia.Overexpressed in a number of carcinomas.Also expressed in Barrett's esophagus epithelium and in the proximal duodenum. |
