MUTYH Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-10477
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
| Synonyms | A/G specific adenine DNA glycosylase,A/G-specific adenine DNA glycosylase,Adenine DNA glycosylase,CYP2C,hMYH,MGC4416,MutY (E. coli) homolog,MutY homolog (E. coli),MutY homolog,MutY,E. coli,homolog of,Mutyh,MUTYH,MYH,rMYH,MUTYH抗体 |
| Swissprot | Q9UIF7 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant protein of human MUTYH |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:1000-1:5000;IHC,,1:50-1:200; |
| Concentration | 0.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene. |
Images
Western Blot analysis of Human liver cancer and stomach cancer tissue using MUTYH Polyclonal Antibody at dilution of 1:1000
Immunohistochemistry of paraffin-embedded Human lung cancer using MUTYH Polyclonal Antibody at dilution of 1:60
Immunohistochemistry of paraffin-embedded Human ovarian cancer using MUTYH Polyclonal Antibody at dilution of 1:60
