MYL12B Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-11220
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | ML12B,MLC 2A,MLC-2,MLC-2a,MLC-B,MLC20,MRLC2,MYL12B,MYLC2B,Myosin light chain 12B regulatory,Myosin regulatory light chain 12B,myosin regulatory light chain 2,Myosin regulatory light chain 2-B,myosin regulatory light chain 2-B,smooth muscle isoform,Myosin regulatory light chain 20 kDa,Myosin regulatory light chain MRLC2,myosin,light chain 12B,regulatory,OTTHUMP00000162244,OTTHUMP00000165806,OTTHUMP00000165807,OTTHUMP00000165808,SHUJUN-1,smooth muscle isoform,MYL12B抗体 |
| Swissprot | O14950 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human MYL12B |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.5 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoskeleton,myosin II complex,stress fiber,Cytosol,Extracellular region or secreted,extracellular exosome,Other locations:apical part of cell,brush border,cell cortex region,Z disc |
| Tissue specificity | Ubiquitously expressed in various hematopoietic cells. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The activity of nonmuscle myosin II (see MYH9; MIM 160775) is regulated by phosphorylation of a regulatory light chain, such as MRLC2.This phosphorylation results in higher MgATPase activity and the assembly of myosin II filaments |
Images
Western Blot analysis of Mouse skeletal muscle, heart and bladder tissue using MYL12B Polyclonal Antibody at dilution of 1:450
Immunohistochemistry of paraffin-embedded Human brain using MYL12B Polyclonal Antibody at dilution of 1:20
Immunohistochemistry of paraffin-embedded Human breast cancer using MYL12B Polyclonal Antibody at dilution of 1:20
