MYOT Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19065
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | 57 kDa cytoskeletal protein,LGMD 1,LGMD1,Myofibrillar titin like Ig domains protein,Myofibrillar titin-like Ig domains protein,Myot,MYOTI,Myotilin,Titin immunoglobulin domain protein,TTID,TTID protein,MYOT抗体 |
| Swissprot | Q9UBF9 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human MYOT |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:1000-1:5000;IHC,,1:50-1:300; |
| Concentration | 1.14mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane>sarcolemma. Cytoplasm>cytoskeleton. Cytoplasm>myofibril>sarcomere>Z line. Sarcomeric, also localized to the sarcolemma. Colocalizes with MYOZ1 at the Z-lines in skeletal muscle. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. |
