NCAPH Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18551
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | Barren Drosophila Homolog of 1,Barren homolog protein 1,BRRN,BRRN1,CAP H,CAPH,Chromosome associated protein H,Chromosome-associated protein H,CND2,Condensin complex subunit 2,Condensin subunit 2,Condensin-2 complex subunit H2,Condesin,HCAP H,hCAP-H,KIAA0074,mCAP H,MGC4616,Ncaph,Non SMC condensin I complex subunit H,Non-SMC condensin I complex subunit H,XCAP H homolog,XCAP-H homolog,NCAPH抗体 |
| Swissprot | Q15003 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human NCAPH |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:30-1:150; |
| Concentration | 0.7mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. Cytoplasm. Chromosome. In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDK1, leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes a member of the barr gene family and a regulatory subunit of the condensin complex. This complex is required for the conversion of interphase chromatin into condensed chromosomes. The protein encoded by this gene is associated with mitotic chromosomes, except during the early phase of chromosome condensation. During interphase, the protein has a distinct punctate nucleolar localization. Alternatively spliced transcript variants encoding different proteins have been described. |
Images
Western blot analysis of 562 and Jurkat cell lysates using NCAPH Polyclonal Antibody at dilution of 1:450
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using NCAPH Polyclonal Antibody at dilution of 1:45(×200)
Immunohistochemistry of paraffin-embedded Human prost ate cancer tissue using NCAPH Polyclonal Antibody at dilution of 1:45(×200)
