NCOR1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-15800
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | hN CoR,hNCoR,KIAA1047,N CoR,N Cor/SMRT corepressor Rip13,N CoR1,N-CoR,N-CoR1,NCOR 1,NCoR,Ncor1,NCOR1,Nuclear receptor co repressor 1,Nuclear receptor corepressor 1,Retinoid X receptor interacting protein 13,RIP13,Rxrip13,thyroid hormone and retinoic acid receptor associated corepressor 1,TRAC 1,TRAC1,NCOR1抗体 |
| Swissprot | O75376 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human NCOR1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:100-1:300 |
| Concentration | 0.6 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20. |
