NCR2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-13122
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | Activating NK receptor NKp44,CD336,CD336 antigen,dJ149M18.1,LY95,Lymphocyte antigen 95 (activating NK receptor,NK p44),Lymphocyte antigen 95 homolog (activating NK receptor,NK p44),Lymphocyte antigen 95 homolog,Lymphocyte antigen 95,mouse,homolog of,Natural cytotoxicity triggering receptor 2,Natural killer cell p44 related protein,Natural killer cell p44-related protein,NCR2,NCTR2,NK cell activating receptor (NKp44),NK cell activating receptor,NK cell-activating receptor,NK p44,NK-p44,NKp44,NCR2抗体 |
| Swissprot | O95944 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human NCR2 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 0.6 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane. |
| Tissue specificity | Selectively expressed by activated NK cells and by in vitro cultured (i.e. activated) TCRg/d lymphoid cells. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Natural cytotoxicity triggering receptor 2 is a protein that in humans is encoded by the NCR2 gene.NCR2 has also been designated as CD336 (cluster of differentiation 336).NKp44 is a natural cytotoxicity receptor that is is expressed on IL-2-activated human NK cells and may contribute to the increased efficiency of NK cells to mediate tumor cell lysis.NKp44 is composed of one Ig-like extracellular domain, a transmembrane segment, and a cytoplasmic domain.Prolactin up-regulates and cortisol down-regulates the surface expression of NKp44 at the transcriptional level.A cellular ligand for NKp44 (NKp44L) is expressed during HIV-1 infection and is correlated with the progression of CD4+ T cell depletion and an increase of viral load. |
