NDUFA13 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-11283
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
Synonyms | 2700054G14Rik,AU022060,B16.6,CDA016,Cell death regulatory protein,Cell death regulatory protein GRIM-19,CGI-39,CGI39 protein,CI-B16.6,Complex I-B16.6,FLJ58045,FLJ59191,Gene associated with retinoic and IFN-induced mortality 19 protein,Gene associated with retinoic and interferon-induced mortality 19 protein,Gene associated with retinoic interferon induced mortality 19 protein,GRIM-19,NADH dehydrogenase (ubiquinone) 1 alpha subcomplex,13,NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13,NADH ubiquinone oxidoreductase B16.6 subunit,NADH-ubiquinone oxidoreductase B16.6 subunit,NDUAD,NDUFA13,RGD1565358,NDUFA13抗体 |
Swissprot | Q9P0J0 |
Source | Rabbit |
Reactivity | Human,Mouse |
Immunogen | Recombinant protein of human NDUFA13 |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:100-1:300; |
Concentration | 0.7 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Mitochondrion inner membrane. Nucleus. May be translocated into the nucleus upon IFN/RA treatment. |
Tissue specificity | Widely expressed, with highest expression in heart, skeletal muscle, liver, kidney and placenta. In intestinal mucosa, down-regulated in areas involved in Crohn disease and ulcerative colitis. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | This gene encodes a subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain. The protein is required for complex I assembly and electron transfer activity. The protein binds the signal transducers and activators of transcription 3 (STAT3) transcription factor, and can function as a tumor suppressor. The human protein purified from mitochondria migrates at approximately 16 kDa. Transcripts originating from an upstream promoter and capable of expressing a protein with a longer N-terminus have been found, but their biological validity has not been determined. |
Images
Western Blot analysis of Mouse skeletal muscle and Human hepatocellular carcinoma tissue using NDUFA13 Polyclonal Antibody at dilution of 1:350
Immunohistochemistry of paraffin-embedded Human ovarian cancer using NDUFA13 Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human colon cancer using NDUFA13 Polyclonal Antibody at dilution of 1:50