NDUFB11 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-52254
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | CI ESSS,Complex I ESSS,complex I NP17.3 subunit,ESSS,FLJ20494,MGC111182,NADH dehydrogenase (ubiquinone) 1 beta subcomplex 11 17.3kDa,NADH dehydrogenase (ubiquinone) 1 beta subcomplex 11,NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11,NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11 mitochondrial,NADH ubiquinone oxidoreductase ESSS subunit,NDUFB 11,Neuronal protein 17.3,Np15,NP17.3,P17.3,NDUFB11抗体 |
| Swissprot | Q9NX14 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Full length fusion protein |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:1000-1:5000;IHC,,1:50-1:300; |
| Concentration | 1.6mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Mitochondrion inner membrane. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Complex 1 (also known as NADH dehydrogenase) of the electron transport chain (respiratory chain) is an enzymatic complex that catalyzes the transfer of electrons from NADH to ubiquinone. Free energy from the reaction is conserved in the transfer of protons into the intermembrane space to create an electrochemical proton gradient, a driving force for ATP synthesis. Complex 1 is a complicated, multi-protein, L-shaped complex composed of at least 45 different subunits and located in the mitochondrial inner membrane. NDUFB11 (NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11), also known as ESSS, Np15, Np17.3 (neuronal protein 17.3) or p17.3, is a hydrophobic transmembrane protein belonging to the Complex I NDUFB11 subunit family. Ubiquitously expressed, NDUFB11 localizes to the inner membrane of the mitochondrion and functions as an accessory subunit of Complex I. The cAMP-dependent phosphorylation of NDUFB11 is important for the regulation of Complex I activity. |
Images
Western blot analysis of Mouse brain tissue Mouse liver tissue 231 cell K562 cell A431 cell lysates using NDUFB11 Polyclonal Antibody at dilution of 1:1000
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using NDUFB11 Polyclonal Antibody at dilution of 1:95(×200)
Immunohistochemistry of paraffin-embedded Human prost ate cancer tissue using NDUFB11 Polyclonal Antibody at dilution of 1:95(×200)
