NECTIN1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-15611
宿主: Rabbit
反应性: H,M
应用: WB
Overview
| Synonyms | CD111,CD111 antigen,CLPED1,ectodermal dysplasia 4 (Margarita Island type),ED4,Herpes virus entry mediator C,Herpesvirus entry mediator C,Herpesvirus Ig like receptor,Herpesvirus Ig-like receptor,HIgR,HveC,MGC142031,Nectin 1,Nectin-1,OFC7,OROFACIAL CLEFT 7,OTTHUMP00000232093,OTTHUMP00000232094,OTTHUMP00000232095,Poliovirus receptor related protein 1,poliovirus receptor-like 1,Poliovirus receptor-related protein 1,PRR,PRR1,PVRL 1,PVRL1,PVRL1,PVRR,PVRR1,SK-12,PVRL1抗体 |
| Swissprot | Q15223 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Synthetic peptide of human PVRL1 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:200-1:1000; |
| Concentration | 0.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted and Cell membrane. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. |
