NEK2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-10922
宿主: Rabbit
反应性: H,M
应用: WB
Overview
| Synonyms | HSPK 21,HsPK21,NEK 2,NEK2,NEK2,NEK2A,Never in mitosis A-related kinase 2,NIMA (never in mitosis gene a) related kinase 2,NimA like protein kinase 1,NIMA related kinase 2,NimA related protein kinase 2,NimA-like protein kinase 1,NimA-related protein kinase 2,NLK 1,NLK1,Serine/threonine-protein kinase Nek2,NEK2抗体 |
| Swissprot | P51955 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Recombinant protein of human NEK2 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Predominantly cytoplasmic; Nucleus>nucleolus. Has a nucleolar targeting/ retention activity via a coiled-coil domain at the C-terminal end and Nucleus. Chromosome>centromere. Chromosome>centromere>kinetochore. Co-localizes with SGOL1 and MAD1L1 at the kinetochore. Not associated with kinetochore in the interphase but becomes associated with it upon the breakdown of the nuclear envelope. |
| Tissue specificity | Isoform 1 and isoform 2 are expressed in peripheral blood T-cells and a wide variety of transformed cell types. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a serine/threonine-protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C-termini have been noted for this gene. |
