NFKBIB Monoclonal Antibody
| 规格： | / 20μL / 60μL / 120μL |
| 价格： | / ￥580 / ￥1420 / ￥2310 |
货号：E-AB-22175
宿主: Mouse
反应性: H,M,R
应用: IHC-p
Overview
| Synonyms | I kappa B beta,I-kappa-B-beta,IkappaBbeta,IKB beta,IkB-B,IkB-beta,IKBB,IKBB,IkBbeta,NF kappa BIB,NF-kappa-B inhibitor beta,NF-kappa-BIB,Nfkbib,Thyroid receptor interacting protein 9,Thyroid receptor-interacting protein 9,TR interacting protein 9,TR-interacting protein 9,TRIP-9,TRIP9,IκB β抗体 |
| Swissprot | Q15653 |
| Source | Mouse |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant Protein |
| Application | IHC-p(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:100-200 |
| Concentration | 1mg/mL |
| Clonality | Monoclonal |
Properties
| Cellular localization | Cytoplasm. Nucleus. |
| Tissue specificity | Expressed in all tissues examined. |
| Isotype | IgG |
| Purification | Protein A purification |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4. |
| Background | Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation. |
