NHP2 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-18904
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
Synonyms | DKCB2,FLJ20479,H/ACA ribonucleoprotein complex subunit 2,NHP2,NHP2 like protein,NHP2 ribonucleoprotein,NHP2 ribonucleoprotein homolog (yeast) 1,NHP2 ribonucleoprotein homolog,NHP2, S. cerevisiae, homolog of,NHP2,NHP2P,NOLA2,Nucleolar protein family A member 2 (H/ACA small nucleolar RNPs),Nucleolar protein family A member 2,snoRNP protein NHP2,NHP2抗体 |
Swissprot | Q9NX24 |
Source | Rabbit |
Reactivity | Human, Mouse |
Immunogen | Fusion protein of human NHP2 |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:300; |
Concentration | 0.96mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Nucleus>nucleolus. Nucleus>Cajal body. Also localized to Cajal bodies. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nhp2p. Alternative splicing results in multiple transcript variants. |
Images
Western blot analysis of Human spleen tissue lysate using NHP2 Polyclonal Antibody at dilution of 1:400
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using NHP2 Polyclonal Antibody at dilution of 1:55(×200)
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using NHP2 Polyclonal Antibody at dilution of 1:55(×200)