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NHP2 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-18904

宿主: Rabbit

反应性: H,M

应用: WB,IHC

  • 详情
  • Overview

    Synonyms DKCB2,FLJ20479,H/ACA ribonucleoprotein complex subunit 2,NHP2,NHP2 like protein,NHP2 ribonucleoprotein,NHP2 ribonucleoprotein homolog (yeast) 1,NHP2 ribonucleoprotein homolog,NHP2, S. cerevisiae, homolog of,NHP2,NHP2P,NOLA2,Nucleolar protein family A member 2 (H/ACA small nucleolar RNPs),Nucleolar protein family A member 2,snoRNP protein NHP2,NHP2抗体
    Swissprot Q9NX24
    Source Rabbit
    Reactivity Human, Mouse
    Immunogen Fusion protein of human NHP2
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213)
    Recommended dilution WB,,1:500-1:2000;IHC,,1:50-1:300;
    Concentration 0.96mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Nucleus>nucleolus. Nucleus>Cajal body. Also localized to Cajal bodies.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nhp2p. Alternative splicing results in multiple transcript variants.
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