NKX2-1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-12670
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
| Synonyms | AV026640,BCH,Benign chorea,BHC,Homeobox protein NK 2 homolog A,Homeobox protein NK-2 homolog A,Homeobox protein Nkx 2.1,Homeobox protein Nkx-2.1,Homeobox protein Nkx2.1,NK 2,NK 2 homolog A,NK2,NK2 homeobox 1,NK2,drosophila,homolog of,A,NK2.1,mouse,homolog of,Nkx 2 1,NKX 2.1,NKX 2A,NKX2 1,Nkx2-1,NKX2.1,NKX21,NKX2A,T EBP,T/EBP,TEBP,Thyroid nuclear factor 1,Thyroid nuclear factor,Thyroid specific enhancer binding protein,Thyroid transcription factor 1,Tin man,Tinman,TITF 1,TITF1,TTF 1,TTF-1,TTF1,NKX2-1抗体 |
| Swissprot | P43699 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human NKX2-1 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.2 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. |
| Tissue specificity | Thyroid and lung. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TFF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. |
