NQO1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-16011
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | Azoreductase,Cytochrome b 5 reductase,DHQU,DIA 4,DIA4,Diaphorase (NADH/NADPH) (cytochrome b 5 reductase),Diaphorase (NADH/NADPH),Diaphorase 4,Dioxin inducible 1,DT diaphorase,DT-diaphorase,DTD,Menadione reductase,NAD(P)H dehydrogenase [quinone] 1,NAD(P)H dehydrogenase quinone 1,NAD(P)H menadione oxidoreductase 1 dioxin inducible,NAD(P)H quinone dehydrogenase 1,NAD(P)H: menadione oxidoreductase 1 dioxin inducible 1,NAD(P)H:menadione oxidoreductase 1,NAD(P)H:Quinone acceptor oxidoreductase type 1,NAD(P)H:quinone oxidoreductase 1,NAD(P)H:quinone oxireductase,NMOR 1,NMOR I,NMOR1,NMORI,NQO 1,NQO1,NQO1,Phylloquinone reductase,QR 1,QR1,Quinone reductase 1,NQO1抗体 |
| Swissprot | P15559 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human NQO1 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
Images
Western Blot analysis of Hela cell using NQO1 Polyclonal Antibody at dilution of 1:600
Immunohistochemistry of paraffin-embedded Human liver cancer using NQO1 Polyclonal Antibody at dilution of 1:25
Immunohistochemistry of paraffin-embedded Human ovarian cancer using NQO1 Polyclonal Antibody at dilution of 1:25
