NRG2 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-19325
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
Synonyms | Divergent of neuregulin 1,Divergent of neuregulin-1,Don 1,DON-1,Neural- and thymus-derived activator for ERBB kinases,Neuregulin 2,Neuregulin-2,NRG-2,Nrg2,NRG2,NTAK,Pro NRG2,Pro-NRG2,NRG2抗体 |
Swissprot | O14511 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Synthetic peptide of human NRG2 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:50-1:300 |
Concentration | 1mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Secreted and Cell membrane. Does not seem to be active. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | This gene encodes a novel member of the neuregulin family of growth and differentiation factors.Through interaction with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells.The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands.The products of these genes mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells.This gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease.Alternative transcript variants encoding distinct isoforms have been described. |