NTRK2 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70155
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
| Synonyms | AI848316,BDNF tropomyosine receptor kinase B,BDNF/NT 3 growth factors receptor,BDNF/NT-3 growth factors receptor,Brain derived neurotrophic factor receptor,C030027L06Rik,EC 2.7.10.1,GP145 TrkB,GP145-TrkB,GP145-TrkB/GP95-TrkB,GP95 TrkB,Neurotrophic receptor tyrosine kinase 2,Neurotrophic tyrosine kinase receptor type 2,Neurotrophin receptor tyrosine kinase type 2,NTRK 2,Ntrk2,NTRK2,Obesity,hyperphagia,and developmental delay,included,RATTRKB1,Tkrb,Trk B,Trk-B,TRKB,TrkB tyrosine kinase,TRKB1,Tropomyosin related kinase B,tyrosine kinase receptor B,Tyrosine receptor kinase B,NTRK2抗体 |
| Swissprot | Q16620,P15209,Q63604 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein corresponding to Mouse TRKB |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 1 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane, Cell projection, Cytoplasm, Endosome, Membrane |
| Tissue specificity | Isoform TrkB is expressed in the central and peripheral nervous system. In the central nervous system (CNS), expression is observed in the cerebral cortex, hippocampus, thalamus, choroid plexus, granular layer of the cerebellum, brain stem, and spinal cord. In the peripheral nervous system, it is expressed in many cranial ganglia, the ophthalmic nerve, the vestibular system, multiple facial structures, the submaxillary glands, and dorsal root ganglia. Isoform TrkB-T1 is mainly expressed in the brain but also detected in other tissues including pancreas, kidney and heart. Isoform TrkB-T-Shc is predominantly expressed in the brain.Highest expression level in hypothalamus. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. |
