NTRK2 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70156
宿主: Rabbit
反应性: M,R
应用: IHC
Overview
| Synonyms | AI848316,BDNF tropomyosine receptor kinase B,BDNF/NT 3 growth factors receptor,BDNF/NT-3 growth factors receptor,Brain derived neurotrophic factor receptor,C030027L06Rik,EC 2.7.10.1,GP145 TrkB,GP145-TrkB,GP145-TrkB/GP95-TrkB,GP95 TrkB,Neurotrophic receptor tyrosine kinase 2,Neurotrophic tyrosine kinase receptor type 2,Neurotrophin receptor tyrosine kinase type 2,NTRK 2,Ntrk2,NTRK2,Obesity,hyperphagia,and developmental delay,included,RATTRKB1,Tkrb,Trk B,Trk-B,TRKB,TrkB tyrosine kinase,TRKB1,Tropomyosin related kinase B,tyrosine kinase receptor B,Tyrosine receptor kinase B,NTRK2抗体 |
| Swissprot | P15209,Q63604 |
| Source | Rabbit |
| Reactivity | Mouse,Rat |
| Immunogen | Recombinant protein corresponding to Mouse TRKB |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:200-1:800 |
| Concentration | 0.6 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane, Cell projection, Cytoplasm, Endosome, Membrane |
| Tissue specificity | Widely expressed in the central and peripheral nervous system. The different forms are differentially expressed in various cell types. Isoform GP95-TRKB is specifically expressed in glial cells.Highest expression level in median eminence of neurohypophysis. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. |
