Otocadherin Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-10530
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC,ELISA
Overview
| Synonyms | Age related hearing loss 1,Ahl 1,Ahl,Ahl1,Bob,Bobby,Bus,Bustling,Cadherin 23,Cadherin23,CDH 23,Mdfw,Modifier of deaf waddler,nmf112,nmf181,nmf252,Otocadherin,USH 1D,USH1 D,USH1D,Waltzer,CDH23抗体 |
| Swissprot | Q9H251 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human CDH23 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA |
| Recommended dilution | WB 1:500-1:2000, IHC 1:100-1:300 |
| Concentration | 0.4 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane; Single-pass type I membrane protein |
| Tissue specificity | Particularly strong expression in the retina. Found also in the cochlea. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Alternative splice variants encoding different isoforms have been described. |
Images
Western Blot analysis of Mouse brain tissue using Otocadherin Polyclonal Antibody at dilution of 1:1050
Immunohistochemistry of paraffin-embedded Human lung cancer using Otocadherin Polyclonal Antibody at dilution of 1:80
Immunohistochemistry of paraffin-embedded Human thyroid cancer using Otocadherin Polyclonal Antibody at dilution of 1:80
