OTUB1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-11463
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
| Synonyms | Deubiquitinating enzyme OTUB1,hOTU1,HSPC263,OTB1,OTU domain containing ubiquitin aldehyde binding protein 1,OTU domain,ubiquitin aldehyde binding 1,OTU domain-containing Ubal-binding protein 1,OTU domain-containing ubiquitin aldehyde-binding protein 1,OTU-domain Ubal-binding 1,OTU1,Otub1,OTUB1,Otubain 1,Otubain-1,Ubiquitin specific processing protease OTUB1,Ubiquitin thioesterase OTUB1,ubiquitin-specific protease otubain 1,Ubiquitin-specific-processing protease OTUB1,OTUB1抗体 |
| Swissprot | Q96FW1 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human OTUB1 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. |
| Tissue specificity | Isoform 1 is ubiquitous. Isoform 2 is expressed only in lymphoid tissues such as tonsils, lymph nodes and spleen, as well as peripheral blood mononuclear cells. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases.The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates.It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system.It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. |
