OXA Polyclonal Antibody
| 规格： | / 25μL / 100μL |
| 价格： | / ￥800 / ￥2100 |
货号：D-AB-10449L
货期：咨询
宿主: Rabbit
反应性: M,R
应用: IHC
Overview
| Synonyms | Hypocretin neuropeptide precursor;Hypocretin;Orexin precursor;Prepro-orexin;Preprohypocretin;HCRT;OX;PPORX;PPOX |
| Swissprot | O43612 |
| Source | Rabbit |
| Reactivity | Mouse,Rat |
| Immunogen | Recombinant Human OXA protein expressed by E.coli |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:1000-1:2000 |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Mitochondrion inner membrane |
| Isotype | IgG |
| Purification | Antigen Affinity Purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,1% BSA and 50% glycerol,pH7.4 |
| Background | OXA1L (OXA1L Mitochondrial Inner Membrane Protein) is a Protein Coding gene. The OXA1L gene,located on 14q11.2,is conserved in chimpanzee,Rhesus monkey,dog,and cow,etc. This gene encodes an evolutionarily conserved protein that is localized to the inner mitochondrial membrane. The encoded protein is essential for the translocation of the N-terminal tail of subunit 2 of cytochrome c oxidase and is involved in the assembly of the cytochrome c oxidase and ATPase complexes of the mitochondrial respiratory chain. In humans,the mitochondrial inner membrane protein Oxa1L is involved in the biogenesis of membrane proteins and facilitates the insertion of both mitochondrial- and nuclear-encoded proteins from the mitochondrial matrix into the inner membrane. The C-terminal approximately 100-amino acid tail of Oxa1L (Oxa1L-CTT) binds to mitochondrial ribosomes and plays a role in the co-translational insertion of mitochondria-synthesized proteins into the inner membrane. |
