PADI4 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-52164
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
| Synonyms | EC 3.5.3.15,HL 60 PAD,HL-60 PAD,PAD 4,PAD,PADI 4,PADI 5,PADI H protein,Padi4,PADI4,PADI5,PDI 4,PDI 5,PDI4,PDI5,Peptidyl arginine deiminase type IV,Peptidyl arginine deiminase type V,Peptidylarginine deiminase IV,Protein arginine deiminase,Protein arginine deiminase type 4,Protein arginine deiminase type IV,Protein-arginine deiminase type IV,Protein-arginine deiminase type-4,PADI4抗体 |
| Swissprot | Q9UM07 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Fusion protein of human PADI4 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:40-1:200; |
| Concentration | 0.6mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Nucleus. Cytoplasmic granule. Cytoplasmic granules of eosinophils and neutrophils. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response. PADI4 plays a role in the epigenetics, the deimination of arginines on histones 3 and 4 can act antagonistically to arginine methylation. The protein may be found in oligomers and binds 5 calcium ions per subunit. It catalyses the reaction: Protein L-arginine + H2O = protein L-citrulline + NH3. |
Images
Western blot analysis of 293T cell lysates using PADI4 Polyclonal Antibody at dilution of 1:400
Immunohistochemistry of paraffin-embedded Human tonsil tissue using PADI4 Polyclonal Antibody at dilution of 1:35(×200)
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PADI4 Polyclonal Antibody at dilution of 1:35(×200)
