PBXIP1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-52665
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | 4732463H20Rik,Hematopoietic PBX interacting protein ,HPIP ,MGC38361,Pre B cell leukemia homeobox interacting protein 1,RP11-307C12.2,PBXIP1抗体 |
| Swissprot | Q96AQ6 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Fusion protein of human PBXIP1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:30-1:150 |
| Concentration | 0.66mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm, cytoskeleton. Nucleus. Note=Shuttles between the nucleus and the cytosol. Mainly localized in the cytoplasm, associated with microtubules. Detected in small amounts in the nucleus. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | The protein encoded by this gene interacts with the PBX1 homeodomain protein, inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein, which is primarily cytosolic but can shuttle to the nucleus, also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer, brain tumors, and lung cancer. Several transcript variants encoding different isoforms have been found for this gene. More variants exist, but their full-length natures have yet to be determined. |
