PCBD1 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-19099
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
Synonyms | 4 alpha hydroxy tetrahydropterin dehydratase,4-alpha-hydroxy-tetrahydropterin dehydratase,6 pyruvoyl tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1),6 pyruvoyl tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha,DCoH,Dimerization cofactor of hepatic nuclear factor 1 alpha,Dimerization cofactor of hepatocyte nuclear factor 1 alpha,Dimerization cofactor of hepatocyte nuclear factor 1-alpha,Dimerization cofactor of HNF1,Dimerizing cofactor for HNF1,PCBD 1,PCBD,PCBD1,PCD,Phenylalanine hydroxylase stimulating protein,Phenylalanine hydroxylase-stimulating protein,PHS,PHS,Pterin 4 alpha carbinolamine dehydratase,Pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1),Pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha,Pterin carbinolamine dehydratase,Pterin-4-alpha-carbinolamine dehydratase,PCBD1抗体 |
Swissprot | P61457 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Fusion protein of human PCBD1 |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:300; |
Concentration | 1.02mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytoplasm. Nucleus. Cytoplasmic and/or nuclear. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | This gene encodes a member of the pterin-4-alpha-carbinolamine dehydratase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein functions as both a dehydratase involved in tetrahydrobiopterin biosynthesis, and as a cofactor for HNF1A-dependent transcription. A deficiency of this enzyme leads to hyperphenylalaninemia. Alternative splicing results in multiple transcript variants. |
Images
Western blot analysis of Mouse kidney tissue lysate using PCBD1 Polyclonal Antibody at dilution of 1:800
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using PCBD1 Polyclonal Antibody at dilution of 1:60(×200)
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PCBD1 Polyclonal Antibody at dilution of 1:60(×200)