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PCK1 Polyclonal Antibody

规格: / 50μL / 100μL
价格: / ¥1010 / ¥1640

货号:D-AB-10224L

货期:咨询

宿主: Rabbit

反应性: H,R

应用: IHC

  • 详情
  • Overview

    Synonyms cytosolic [GTP],GTP,PCK1,PCKGC,PEP carboxykinase,PEPCK-C,PEPCK1,PEPCKC,Phosphoenolpyruvate carboxykinase 1 (soluble),Phosphoenolpyruvate carboxykinase 1,Phosphoenolpyruvate carboxykinase,Phosphoenolpyruvate carboxykinase,cytosolic [GTP],Phosphoenolpyruvate carboxykinase,cytosolic,Phosphoenolpyruvate carboxylase,Phosphopyruvate carboxylase,PCK1抗体
    Swissprot P07379
    Source Rabbit
    Reactivity Human,Rat
    Immunogen Recombinant Rat PCK1 protein expressed by E.coli
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:100-1:200
    Concentration 1mg/mL
    Clonality Polyclonal

    Properties

    Isotype IgG
    Purification Antigen Affinity Purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4
    Background This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene,along with GTP,catalyzes the formation of phosphoenolpyruvate from oxaloacetate,with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin,glucocorticoids,glucagon,cAMP,and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.
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