PDCD4 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-52165
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | Death up-regulated gene protein,Dug,H731,Ma3,MGC33046,MGC33047,Neoplastic transformation inhibitor,Neoplastic transformation inhibitor protein,Nuclear antigen H731,Nuclear antigen H731 like,Nuclear antigen H731 like protein,Nuclear antigen H731-like,PDCD 4,Pdcd4,PDCD4,Programmed cell death 4,programmed cell death 4 (neoplastic transformation inhibitor),Programmed cell death protein 4,Protein 197/15a,Protein MA-3,Tis,Topoisomerase-inhibitor suppressed protein,PDCD4抗体 |
| Swissprot | Q53EL6 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Fusion protein of human PDCD4 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:40-1:200; |
| Concentration | 0.6mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. Cytoplasm. Shuttles between the nucleus and cytoplasm. Predominantly nuclear under normal growth conditions, and when phosphorylated at Ser-457. Exported from the nucleus in the absence of serum. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Programmed cell death 4 (Pdcd4) is a novel tumor suppressor that inhibits translation,progression and invasion. It was first identified as being differnetially upregulated during apoptosis. Pdcd4 interferes with the activity of the eukaryotic initiation factor (eIF) 4A by displacing the scaffold protein eIF4G from its binding to the RNA helicase eIF4A. |
