PDE4D Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-10534
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
| Synonyms | cAMP specific 3',5' cyclic phosphodiesterase 4D, DKFZp686M11213,5''-cyclic phosphodiesterase 4D,cAMP specific phosphodiesterase 4D,cAMP specific phosphodiesterase PDE4D6,cAMP-specific 3'',DPDE3,Dunce like phosphodiesterase E3,FLJ97311,HSPDE4D,PDE43,Pde4d,PDE4D,PDE4DN2,Phosphodiesterase 4D cAMP specific (dunce (Drosophila) homolog phosphodiesterase E3),Phosphodiesterase 4D cAMP specific (phosphodiesterase E3 dunce homolog Drosophila),Phosphodiesterase 4D cAMP specific,Phosphodiesterase 4D,cAMP specific (dunce),STRK1,PDE4D抗体 |
| Swissprot | Q08499 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant protein of human PDE4D |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.2 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Membrane. Cytoplasm>cytoskeleton. Cytoplasm>cytoskeleton>centrosome. Found in the soluble fraction, associated with membranes, and associated with the cytoskeleton and the centrosome. |
| Tissue specificity | Widespread; most abundant in skeletal muscle. Isoform 6 is detected in brain. Isoform 8 is detected in brain, placenta, lung and kidney. Isoform 7 is detected in heart and skeletal muscle. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins. |
Images
Western Blot analysis of Human bladder carcinoma tissue and A172 cell, Human fetal brain tissue and hela cell using PDE4D Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human gastic cancer using PDE4D Polyclonal Antibody at dilution of 1:20
Immunohistochemistry of paraffin-embedded Human thyroid cancer using PDE4D Polyclonal Antibody at dilution of 1:20
