PERK Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70363
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | DKFZp781H1925,E2AK3,EC 2.7.11.1,Eif2ak3,Eukaryotic translation initiation factor 2 alpha kinase 3,Eukaryotic translation initiation factor 2-alpha kinase 3,Heme regulated EIF2 alpha kinase,HRI,HsPEK,Pancreatic eIF2 alpha kinase,Pancreatic eIF2-alpha kinase,PEK,PRKR like endoplasmic reticulum kinase,PRKR-like endoplasmic reticulum kinase,WRS,PERK抗体 |
| Swissprot | Q9NZJ5 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Human PERK |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:400-1000 |
| Concentration | 1.4 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Endoplasmic reticulum membrane. |
| Tissue specificity | Ubiquitous. A high level expression is seen in secretory tissues. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis.It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins.Mutations in this gene are associated with Wolcott-Rallison syndrome. |
Images
Immunohistochemistry analysis of paraffin-embedded human tonsil using PERK Polyclonal Antibody at dilution of 1:400.
Immunohistochemistry analysis of paraffin-embedded human lung cancer using PERK Polyclonal Antibody at dilution of 1:400.
Immunohistochemistry analysis of paraffin-embedded human liver cancer using PERK Polyclonal Antibody at dilution of 1:400.
Immunohistochemistry analysis of paraffin-embedded human colon using PERK Polyclonal Antibody at dilution of 1:500.
