PFKM Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-52666
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | 6 Phosphofructokinase Muscle Type,6-phosphofructokinase,6-phosphofructokinase muscle type,EC 2.7.1.1,EC 2.7.1.11,GSD7,K6PF,MGC8699,muscle type,PFK,muscle type,PFK-A,PFKA,PFKL,PFKM,PFKP,PFKX,Phosphofructo 1 Kinase Isozyme A,Phosphofructo-1-kinase isozyme A,Phosphofructokinase 1,Phosphofructokinase M,Phosphofructokinase,muscle,Phosphofructokinase,muscle type,Phosphofructokinase,polypeptide X,Phosphofructokinase-M,Phosphohexokinase,PFKM抗体 |
| Swissprot | P08237 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Fusion protein of human PFKM |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:40-1:200 |
| Concentration | 0.9mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytosol,6-phosphofructokinase complex,cytosol,Extracellular region or secreted,extracellular exosome,Nucleus,Plasma Membrane,apical plasma membrane,Other locations:sperm principal piece |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described. |
