PGP 9.5 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70251
宿主: Rabbit
反应性: M,R
应用: WB
Overview
| Synonyms | Epididymis luminal protein 117,Epididymis secretory protein Li 53,HEL 117,HEL S 53,NDGOA,Neuron cytoplasmic protein 9.5,OTTHUMP00000218137,OTTHUMP00000218139,OTTHUMP00000218140,OTTHUMP00000218141,Park 5,PARK5,PGP 9.5,PGP9.5,PGP95,Protein gene product 9.5,Ubiquitin C terminal esterase L1,Ubiquitin C terminal hydrolase,Ubiquitin C terminal hydrolase L1,Ubiquitin carboxyl terminal esterase L1,Ubiquitin carboxyl terminal hydrolase isozyme L1,Ubiquitin carboxyl-terminal hydrolase isozyme L1,Ubiquitin thioesterase L1,Ubiquitin thiolesterase,Ubiquitin thiolesterase L1,UCH-L1,UCHL1,UCHL1,PGP 9.5抗体 |
| Swissprot | Q9R0P9,Q00981 |
| Source | Rabbit |
| Reactivity | Mouse,Rat |
| Immunogen | Recombinant protein corresponding to Mouse PGP9.5 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 340 μg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm |
| Tissue specificity | Expressed in brain, where it is found in neurons but not in oligodendrocytes or astrocytes. Found in the ganglion cell layer and the inner nuclear layer of the retina (at protein level). Expressed in brain and testis. In the brain, expression is at its lowest in replaceable neurons of hippocampus and olfactory bulb. Highly expressed in senescent pituitary.Highest expression level in dorsal root ganglion. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | UCHL1(Ubiquitin carboxyl-terminal hydrolase isozyme L1) is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCHL1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is present in all neurons. This protein is present in brain at concentrations at least 50 times greater than in other organs and is a major protein component of neuronal cytoplasm . And UCHL1 is a Parkinson's disease susceptibility gene . |
