PGP 9.5 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70268
宿主: Rabbit
反应性: M,R
应用: WB,IHC
Overview
| Synonyms | Epididymis luminal protein 117,Epididymis secretory protein Li 53,HEL 117,HEL S 53,NDGOA,Neuron cytoplasmic protein 9.5,OTTHUMP00000218137,OTTHUMP00000218139,OTTHUMP00000218140,OTTHUMP00000218141,Park 5,PARK5,PGP 9.5,PGP9.5,PGP95,Protein gene product 9.5,Ubiquitin C terminal esterase L1,Ubiquitin C terminal hydrolase,Ubiquitin C terminal hydrolase L1,Ubiquitin carboxyl terminal esterase L1,Ubiquitin carboxyl terminal hydrolase isozyme L1,Ubiquitin carboxyl-terminal hydrolase isozyme L1,Ubiquitin thioesterase L1,Ubiquitin thiolesterase,Ubiquitin thiolesterase L1,UCH-L1,UCHL1,UCHL1,PGP 9.5抗体 |
| Swissprot | P09936,Q9R0P9,Q00981 |
| Source | Rabbit |
| Reactivity | Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse PGP9.5 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:300-1:800; |
| Concentration | 1.8 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm |
| Tissue specificity | Found in neuronal cell bodies and processes throughout the neocortex (at protein level). Expressed in neurons and cells of the diffuse neuroendocrine system and their tumors. Weakly expressed in ovary. Down-regulated in brains from Parkinson disease and Alzheimer disease patients.Highest expression level in anterior cingulate cortex. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | UCHL1(Ubiquitin carboxyl-terminal hydrolase isozyme L1) is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCHL1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is present in all neurons. This protein is present in brain at concentrations at least 50 times greater than in other organs and is a major protein component of neuronal cytoplasm . And UCHL1 is a Parkinson's disease susceptibility gene . |
Images
Western Blot analysis of various samples using PGP 9.5 Polyclonal Antibody at dilution of 1:600.
Immunohistochemistry analysis of paraffin-embedded mouse brain using PGP 9.5 Polyclonal Antibody at dilution of 1:500.
Immunohistochemistry analysis of paraffin-embedded rat brain using PGP 9.5 Polyclonal Antibody at dilution of 1:500.
