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PHF6 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-52168

宿主: Rabbit

反应性: H,M

应用: IHC

  • 详情
  • Overview

    Synonyms AC004383.6,BFLS,BORJ,CENP 31,Centromere protein 31,MGC14797,OTTHUMP00000024063,PHD finger protein 6,PHD like zinc finger protein,PHD-like zinc finger protein,Phf6,PHF6,PHF6抗体
    Swissprot Q8IWS0
    Source Rabbit
    Reactivity Human, Mouse
    Immunogen Fusion protein of human PHF6
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:100-1:300
    Concentration 1.5mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Nucleus. Nucleus>nucleolus. Nuclear, it particularly localizes to the nucleolus.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background This gene is a member of the plant homeodomain (PHD)-like finger (PHF) family.It encodes a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus.Mutations affecting the coding region of this gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by cognitive disability, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears.Alternate splicing results in multiple transcript variants, encoding different isoforms.
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