Phospho-SMAD2/3 (Thr8) Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL |
| 价格： | / ￥630 / ￥1510 / ￥2415 |
货号：E-AB-21040
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
| Synonyms | SMAD2,MADH2,MADR2,Mothers against decapentaplegic homolog 2,MAD homolog 2,Mothers against DPP homolog 2,JV18-1,Mad-related protein 2,hMAD-2,SMAD family member 2,SMAD 2,Smad2,hSMAD2,SMAD3,MADH3,Mothers against decapentaplegic,Smad2/3 (phospho Thr8)磷酸化抗体 |
| Swissprot | Q15796,P84022 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthesized peptide derived from human Smad2/3 around the phosphorylation site of Thr8 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytosol,Nucleus,heteromeric SMAD protein complex,nuclear chromatin,nuclear inner membrane,nucleoplasm,nucleus,Plasma Membrane,Other locations:cytoplasm,receptor complex,SMAD protein complex,transcription factor complex |
| Tissue specificity | SMAD2 is Expressed at high levels in skeletal muscle, endothelial cells, heart and placenta. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
| Background | SMAD is a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. They mediate the signal of the transforming growth factor (TGF)-beta, and thus regulate multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. |
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