PIKFYVE Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-10902
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | 1 phosphatidylinositol 3 phosphate 5 kinase,1 phosphatidylinositol 4 phosphate 5 kinase,1-phosphatidylinositol 3-phosphate 5-kinase,CFD,epididymis luminal protein 37,FAB1,FAB1,S. cerevisiae,homolog of,FYV1,FYVE finger containing phosphoinositide kinase,FYVE finger-containing phosphoinositide kinase,KIAA0981,MGC40423,p235,Phosphatidylinositol 3 phosphate 5 kinase type III,Phosphatidylinositol 3 phosphate/phosphatidylinositol 5 kinase type III,Phosphatidylinositol 3-phosphate 5-kinase,Phosphatidylinositol 3-phosphate 5-kinase type III,Phosphatidylinositol 4 phosphate 5 kinase type III,Phosphoinositide kinase,FYVE finger containing,PIKfyve,PIP5K,PIP5K3,PIPkin III,PIPkin-III,PtdIns(4)P 5 kinase,Type III PIP kinase,ZFYVE29,Zinc finger,FYVE domain containing 29,PIKFYV抗体 |
| Swissprot | Q9Y2I7 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Recombinant protein of human PIKFYV |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 0.4 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Endosome membrane. Mainly associated with membranes of the late endocytic pathway. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Phosphorylated derivatives of phosphatidylinositol (PtdIns) regulate cytoskeletal functions, membrane trafficking, and receptor signaling by recruiting protein complexes to cell- and endosomal-membranes. Humans have multiple PtdIns proteins that differ by the degree and position of phosphorylation of the inositol ring. This gene encodes an enzyme (PIKfyve; also known as phosphatidylinositol-3-phosphate 5-kinase type III or PIPKIII) that phosphorylates the D-5 position in PtdIns and phosphatidylinositol-3-phosphate (PtdIns3P) to make PtdIns5P and PtdIns(3,5)biphosphate. |
