PIP5K1C Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-13020
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
| Synonyms | Diphosphoinositide kinase,LCCS3,Phosphatidylinositol-4-phosphate 5-kinase type I gamma,Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma,PI51C,PI51C,PIP5K GAMMA,PIP5K1-gamma,Pip5k1c,PIP5KIgamma,PtdIns(4)P 5 kinase gamma,PtdIns(4)P-5-kinase 1 gamma,Type I PIP kinase,PIP5K1C抗体 |
| Swissprot | O60331 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human PIP5K1C |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:200-1:1000; |
| Concentration | 0.1 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane. Cytoplasmic, associated with the plasma membrane. Detected in focal adhesion plaques, membrane ruffles and plasma membrane invaginations. |
| Tissue specificity | Isoform 1 is strongly expressed in brain and also detected in heart and lung. Isoform 2 is strongly expressed in pancreas and liver and in lesser quantities in brain, heart, lung and kidney. Isoform 3 is detected in large amounts in heart and large intestine, is also present in lung, pancreas and thyroid, and to a lesser extent in brain, stomach and kidney. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This locus encodes a type I phosphatidylinositol 4-phosphate 5-kinase. The encoded protein catalyzes phosphorylation of phosphatidylinositol 4-phosphate, producing phosphatidylinositol 4,5-bisphosphate. This enzyme is found at synapses and has been found to play roles in endocytosis and cell migration. Mutations at this locus have been associated with lethal congenital contractural syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. |
